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AH RA LEE MIN SU LEE IN SEONG JUNG DAE YOUNG KIM SANG SEOP NHAM HYUN WOO CHUNG KIDONG EOM 《Veterinary radiology & ultrasound》2010,51(2):145-147
An 8‐year‐old Shih Tzu developed abdominal pain and hyperglobulinemia. A round splenic mass was noted radiographically and sonographically. The patient was evaluated by fluorodeoxyglucose positron emission tomography coupled with computed tomography (FDG‐PET/CT). There was no evidence of metastasis or bone marrow involvement on PET/CT images. The standardized uptake value (SUV) of the splenic mass was increased over the reference range (SUV=4.83). The patient was diagnosed as splenic extramedullary plasmacytoma through immunohistopathologic study. After the splenectomy, the globulin level normalized and the patient is alive without complications. 相似文献
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MIN SU LEE JEFF KO AH RA LEE IN HYE LEE MI AE JUNG BRENDA AUSTIN HYUNWOO CHUNG SANGSOEP NAHM KIDONG EOM 《Veterinary radiology & ultrasound》2010,51(2):130-135
The purpose of this study was to assess the effects of four anesthetic protocols on normal canine brain uptake of 2‐deoxy‐2‐[18F]fluoro‐d ‐glucose (FDG) using positron emission tomography/computed tomography (PET/CT). Five clinically normal beagle dogs were anesthetized with (1) propofol/isoflurane, (2) medetomidine/pentobarbital, (3) xylazine/ketamine, and (4) medetomidine/tiletamine–zolazepam in a randomized cross‐over design. The standard uptake value (SUV) of FDG was obtained in the frontal, parietal, temporal and occipital lobes, cerebellum, brainstem and whole brain, and compared within and between anesthetic protocols using the Friedman test with significance set at P<0.05. Significant differences in SUVs were observed in various part of the brain associated with each anesthetic protocol. The SUV for the frontal and occipital lobes was significantly higher than in the brainstem in all dogs. Dogs receiving medetomidine/tiletamine–zolazepam also had significantly higher whole brain SUVs than the propofol/isoflurane group. We concluded that each anesthetic protocol exerted a different regional brain glucose uptake pattern. As a result, when comparing brain glucose uptake using PET/CT, one should consider the effects of anesthetic protocols on different regions of the glucose uptake in the dog's brain. 相似文献
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Functional imaging using positron emission tomography (PET) plays an important role in the diagnosis, staging, image‐guided treatment planning and monitoring of malignant diseases. PET imaging complements conventional anatomical imaging such as computed tomography (CT) and magnetic resonance imaging (MRI). The strength of CT scanning lies in its high spatial resolution, allowing for anatomical characterization of disease. PET imaging, however, moves beyond anatomy and characterizes tissue based on functions such as metabolic rate. Combined PET/CT scanners were introduced commercially in 2001 and a number of technological advancements have since occurred. Radiolabelled tracers such as 18F‐fluorodeoxyglucose (FDG) and 18F‐fluorothymidine (FLT) allow visualization of various metabolic processes within cancer cells. Many studies in human oncology evaluating the utility of PET/CT have demonstrated clinical benefits. Few veterinary studies have been performed, but initial studies show promise for improved detection of malignancy, more thorough staging of canine cancer and determination of early response and disease recrudescence. 相似文献
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A novel resonator for accelerometer with sensing and actuating combs was designed and fabricated based on micro electromechanical system (MEMS) process. Driving force and demand voltage of the resonator were analyzed by analytical method and Finite Element Method (FEM). Sensing capacitance on resonance state and Q factor under atmosphere was calculated by these two methods. The micro fabrication process was planned and realized using MEMS (Micro electromechanical System) method. The testing results show the performance of the resonator is high; the natural frequency of the resonator is 54 523.5 Hz, which has the error of 13.6% with the theorical value. 相似文献
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In order to study the effects of different catalytic walls on combustion characteristics, the premixed catalytic combustion characteristics of methane/air in micro combustor are studied. It lays the foundation for the combustion technology of hydrocarbon fuel in micro engine. Numerical simulation of flow and catalytic combustion in micro combustor was done by using laminar finite rate and second order upwind discretization methods. The results show that when wall temperature,CH4/O2 mole ratio and methane mass flow rate change, the influence of lower catalytic wall on the methane catalytic combustion efficiency is biggest, followed by side catalytic wall, the smallest is upper catalytic wall. The methane catalytic combustion efficiency unit area of lower catalytic wall is about three times of that of upper catalytic wall. The utilization of catalyst on lower catalytic wall is maximal . Therefore, when coating catalyst, the quantity of katalyst on lower catalytic wall should be appropriate more, moderate on the side catalytic wall, as little as possible on the upper catalytic wall. The influence disciplinarian and contribution rate of different catalytic wall on methane combustion have been gained. The optimized strategy of catalyst coating was put forward and reduced the cost of catalytic combustion. 相似文献
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东亚钳蝎神经毒素BmK CT三维结构分子建模及晶体生长条件的初步筛选 总被引:1,自引:0,他引:1
东亚钳蝎是一类广泛分布于我国且具有重要药用价值的野生资源.其氯离子通道神经毒素(BmK CT)对人脑神经胶质瘤细胞具有靶向特异性的抑制作用.利用SWISS-MODEL服务器对BmK CT进行蛋白质原子结构的同源建模,利用Insight II软件包对建模结果做能量最小化和分子动力学优化,获得最佳候选模型.三维结构对比分析表明,BmK CT与以色列蝎氯通道毒素(Cltx)三维结构极为相似,均由一个α-helix和两个反向平行的β-sheet构成,但BmK CT属于βαβ型,而Cltx属于αββ型.表面静电势分析表明,BmK CT和Cltx分子表面分布着大量正电势,暗示两分子功能相似,且其中的碱性氨基酸及产生的正电势对其与受体结合起决定作用.采用晶体生长试剂盒(Crystal Screening Kit)中的51个缓冲液配方筛选BmK CT的结晶条件,在7号配方(1.4 mol/L 乙酸钠,0.1 mol/L 甲次砷酸钠,pH 6.51中筛选到柱状六边形晶体. 相似文献
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目的分析霉菌性副鼻窦炎CT的表现和特征,了解CT诊断对该病的意义。方法对10例经手术及病理证实的霉菌性副鼻窦炎的CT征象作临床回顾性分析。结果霉菌性副鼻窦炎CT主要为单侧或双侧多个鼻窦窦腔内填充软组织密度影,但以上颌窦为主和单侧多见;窦腔密度增高、不均匀、呈絮状,平均CT值为55~70Hu,其腔内可见斑点状、云絮状、条带状高密度钙化影,窦壁多呈反应性增厚。部分病例伴有鼻窦骨质吸收破坏。结论病变内钙化影是霉菌性副鼻窦炎CT的主要表现,是诊断该病较为可靠的依据。 相似文献
50.
DMLS微换热器粗糙度对Al2O3/R141b流动沸腾传热影响 总被引:1,自引:0,他引:1
为了探究DMLS(直接金属激光烧结)微型换热器换热通道表面粗糙度对纳米流体制冷剂流动沸腾传热的影响,运用化学抛光技术改变不同DMLS微型换热器换热管道表面的粗糙度,制备0.01%低浓度Al2O3/R141b纳米流体制冷剂为实验工质,在不同的热流密度9.4~29.4 k W/m2、质量流率184.3~432.2 kg/(m2·s)下,研究不同DMLS换热管道表面下的粗糙度对Al2O3/R141b流动沸腾传热特性。研究结果表明:粗糙度对纳米流体制冷剂在DMLS微型换热器内流动沸腾传热有显著影响,纳米流体制冷剂的换热性能随粗糙度的减小而减弱,粗糙度减小80.4%,换热性能减弱22.5%;相同的工况下,相比于表面粗糙度为8.7μm DMLS微型换热器换热管道,纳米流体制冷剂在粗糙度为5.8、3.2、1.7μm DMLS微型换热器换热管道中的平均换热系数分别减小7.1%、14.1%、22.5%;DMLS微型换热器换热通道表面粗糙度越大,表面凹凸程度越大,单位长度换热通道内,纳米流体制冷剂与通道表面有更多的接触面积,促使单位面积上有更多的纳米制冷剂核气化核心密度,同时核化起点提前、壁面过热程度越低,有利于强化传热效果;实验结果与修正后的LAZAREK传热模型结果相对偏差为9.88%,验证了数学模型的有效性及实验结果的可靠性。 相似文献